ოთხშაბათი, აპრილი 15, 2026
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Global Ingredient Risk Index Specialty

Oats

Avena sativa

Also known as: Whole oat, Avena sativa grain, Oatmeal

LOW RISK 1.0/10 How?

This ingredient is classified as unclassified risk.

02

Safety Profile

Information not yet available for this ingredient profile.

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03

Interactions

Information not yet available for this ingredient profile.

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04

Evidence and Scientific Findings

Overview

Ingredient Overview

Oats are a whole grain with excellent safety record as a food. Contains beta-glucan for cholesterol management. Individuals with coeliac disease should use certified gluten-free oat products.

Classification

Biological and Chemical Classification

Scientific Name
Avena sativa
Mechanism

Mechanism of Action

Information not yet available for this ingredient profile.

Clinical Evidence

Clinical Evidence of Effectiveness

Information not yet available for this ingredient profile.

Pharmacokinetics

Pharmacokinetics

Information not yet available for this ingredient profile.

Dosage

Recommended Dosage

Information not yet available for this ingredient profile.

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05

SETI — Scientific Evidence Transparency Index

SETI Score 50/100
Risk Level High risk
Scientific Confidence Low
Evidence Strength Limited
Key Benefit Specialty
Evidence Reviewed 10 PubMed studies
Scientific Confidence Low
Based on study quality, consistency, and recency

Executive Summary — Ingredient Assessment

SETI Score 50/100
Risk Level High risk
Evidence Strength Limited
Main Benefit Specialty
Ingredient Oats
Scientific name Avena sativa
Scientific Evidence Overview
  • 10 studies reviewed
  • 0 high-quality studies (meta-analysis or RCT)
  • Main clinical benefit observed: Specialty
  • Evidence consistency: High consistency across studies (100%)
Safety Signals
  • No significant safety signals identified in the reviewed literature.
Evidence Strength Limited
Final Scientific Assessment

The available scientific evidence for Oats indicates notable safety signals that warrant caution. Use should be considered carefully and monitored, particularly in sensitive populations or alongside other medications.

Ingredient Oats
Evidence reviewed 10 peer-reviewed studies (last 10 years)
Scientific name Avena sativa
50 /100

Total SETI Score

High risk
Evidence quality 10/40
Evidence consistency 20/20
Safety signals 0/20
Study recency 10/10
Evidence transparency 10/10

Evidence Summary

  • 10 studies reviewed
  • 0 high-quality studies (meta-analysis or systematic review)
  • 0 studies identified benefits or no safety concern (GREEN)
  • 10 studies reported limited or advisory safety evidence (YELLOW)

Evidence Policy

Only peer-reviewed scientific literature indexed in PubMed or comparable databases is included in this evaluation. Commercial websites, blogs, and marketing materials are excluded. All references include direct traceable links to source documents.

Last updated: 06 აპრ 2026, 12:12

Evidence Distribution

10 Other / unclassified
  1. Observational / other LOW evidence YELLOW
    GWAS and genomic prediction of crown rust resistance in the southern US elite oat (Avena sativa L.) germplasm. ↗
    PMID 41906791 ↗
    Journal Plant Genome
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41906791/
    Acharya JP et al.. GWAS and genomic prediction of crown rust resistance in the southern US elite oat (Avena sativa L.) germplasm.. Plant Genome. 2026. PMID:41906791.
  2. Observational / other LOW evidence YELLOW
    Leaf Position-Specific Photosynthetic and Metabolic Adaptations Underpin Saline-Alkali Stress Tolerance in Oats (Avena sativa L.). ↗
    PMID 41902790 ↗
    Journal J Agric Food Chem
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41902790/
    Li X et al.. Leaf Position-Specific Photosynthetic and Metabolic Adaptations Underpin Saline-Alkali Stress Tolerance in Oats (Avena sativa L.).. J Agric Food Chem. 2026. PMID:41902790.
  3. Observational / other LOW evidence YELLOW
    Assessment of Heavy Metal Accumulation in Soils and Dominant Agricultural Crops in an Industrial Environment of Ridder, East Kazakhstan Region. ↗
    PMID 41901501 ↗
    Journal Plants (Basel)
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41901501/
    Daurov D et al.. Assessment of Heavy Metal Accumulation in Soils and Dominant Agricultural Crops in an Industrial Environment of Ridder, East Kazakhstan Region.. Plants (Basel). 2026. PMID:41901501.
  4. Observational / other LOW evidence YELLOW
    Genome-Wide Association Study on Lodging Resistance-Related Traits in Oats. ↗
    PMID 41901380 ↗
    Journal Plants (Basel)
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41901380/
    Zhao L et al.. Genome-Wide Association Study on Lodging Resistance-Related Traits in Oats.. Plants (Basel). 2026. PMID:41901380.
  5. Observational / other LOW evidence YELLOW
    Genome-Wide Identification and Functional Studies of the APX Gene Family in Oat (Avena sativa L.). ↗
    PMID 41901012 ↗
    Journal Life (Basel)
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41901012/
    Li C et al.. Genome-Wide Identification and Functional Studies of the APX Gene Family in Oat (Avena sativa L.).. Life (Basel). 2026. PMID:41901012.
  6. Observational / other LOW evidence YELLOW
    Exploring Nutritional Quality and Bioactive Compounds in Oat Mediterranean Landraces and Cultivars. ↗
    PMID 41897487 ↗
    Journal Antioxidants (Basel)
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41897487/
    Prats E et al.. Exploring Nutritional Quality and Bioactive Compounds in Oat Mediterranean Landraces and Cultivars.. Antioxidants (Basel). 2026. PMID:41897487.
  7. Observational / other LOW evidence YELLOW
    Integrated assessment of selectivity, soil behavior, and biochar-mediated release for the botanical herbicide precursor S-(-)-Spirobrassinin. ↗
    PMID 41884434 ↗
    Journal Front Plant Sci
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41884434/
    Wang Y et al.. Integrated assessment of selectivity, soil behavior, and biochar-mediated release for the botanical herbicide precursor S-(-)-Spirobrassinin.. Front Plant Sci. 2026. PMID:41884434.
  8. Observational / other LOW evidence YELLOW
    Editorial: Strategies for crops to confront extreme weather and pests/diseases. ↗
    PMID 41836056 ↗
    Journal Front Genet
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41836056/
    Wang L et al.. Editorial: Strategies for crops to confront extreme weather and pests/diseases.. Front Genet. 2026. PMID:41836056.
  9. Observational / other LOW evidence YELLOW
    Different application methods of humic acid and zinc differentially regulate osmotic balance and C-repeat binding factor pathways in cold-stressed oat (Avena sativa… ↗
    PMID 41809692 ↗
    Journal PeerJ
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41809692/
    Kutlu I et al.. Different application methods of humic acid and zinc differentially regulate osmotic balance and C-repeat binding factor pathways in cold-stressed oat (Avena sativa L.).. PeerJ. 2026. PMID:41809692.
  10. Observational / other LOW evidence YELLOW
    Chemical characterization of Nurexan: composition of a multicomponent natural veterinary medicinal product. ↗
    PMID 41800299 ↗
    Journal Front Vet Sci
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41800299/
    Duller S et al.. Chemical characterization of Nurexan: composition of a multicomponent natural veterinary medicinal product.. Front Vet Sci. 2026. PMID:41800299.
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06

Score Transparency

Q × L × D × S × 10 = 1.0 / 10

The GIRI Score is the product of four independently computed evidence components, each normalised to 0–1, then scaled to 0–10. Every component is derived exclusively from peer-reviewed references and regulatory data — no editorial judgement is applied.

Q
Evidence Quantity 0 / 10
0%

0 of 10 approved references (score saturates at 10). More peer-reviewed studies = stronger evidence base.

Method: Q = number of approved references ÷ 10 (capped at 1.0)

L
Evidence Quality 5 / 10
50%

Limited — mostly case reports or animal studies

Method: L = mean study-level weight across approved references. Level 1 (meta-analysis / systematic review) = 1.0; Level 2 (RCT) = 0.8; Level 3 (cohort/case-control) = 0.6; Level 4 (case report) = 0.4; Level 5 (animal / in-vitro) = 0.2.

D
Evidence Direction 5 / 10
Benefit
Risk
50%

Mixed or neutral — roughly equal benefit and risk signals

Method: D = (sum of risk-scored references − sum of benefit-scored references) ÷ total evidence score, then scaled from [−1, 1] to [0, 1]. 0.0 = pure benefit; 0.5 = neutral; 1.0 = pure risk.

S
Safety Signals 5 / 10
50%

One or more monitoring-level safety signals active

Method: S = 0.5 (neutral baseline) + sum of active signal severity deltas ÷ 10. Severity deltas: Critical = +2.0, High = +1.5, Moderate = +1.0, Low = +0.5. Capped at 1.0.

0Q × 5L × 5D × 5S = 1.0 / 10

Final GIRI Score for Oats. Risk level thresholds: Low 0–3.0 · Moderate 3.0–5.5 · High 5.5–7.5 · Critical 7.5–10.

Full methodology & data sources

The GIRI Score is computed entirely from structured data — no editorial scoring or subjective weighting is applied at any step.

  • References: Only approved references are counted. Each reference is assigned an evidence level (L1–L5) and a direction (risk / neutral / benefit) by the reference manager or AI classifier.
  • Safety Signals: Sourced from regulatory agencies (FDA, EMA, Health Canada, TGA, and others) and pharmacovigilance databases. Only active signals count toward the score.
  • Formula version: GIRI Score v3.7.0 — Q × L × D × S × 10.
  • Limitations: The score reflects published evidence and recorded signals as of the last update date. It is not a clinical risk assessment and should not replace advice from a qualified healthcare professional.
07

Risk Level Classification

LOW RISK 1.0/10

Based on available regulatory signals and scientific evidence, this ingredient presents a low safety concern under normal conditions of use.

LOW
0–3.0
MODERATE
3.0–5.5
HIGH
5.5–7.5
CRITICAL
7.5–10
1.0

The score pin shows exactly where this ingredient falls on the fixed risk scale.

What drove the Low classification for Oats

GIRI Score 1.0 / 10

A score of 1.0 places this ingredient in the Low band. Thresholds: Low 0–3.0 · Moderate 3.0–5.5 · High 5.5–7.5 · Critical 7.5–10.

Evidence Quantity (Q) 0 / 10 refs

0 approved references.

Evidence Quality (L) 50%

Limited — mostly case reports or animal studies (Level 4–5).

Evidence Direction (D) 50% toward risk

Neutral or mixed — benefit and risk signals roughly balanced.

Safety Signals (S) 0 active signals

No active signals — S component is at neutral baseline (0.5), contributing no extra risk weight.

Regulatory Status No restrictions found

No major regulatory restrictions or advisories recorded across monitored jurisdictions (FDA, EMA, Health Canada, TGA, and others).

How are the Low / Moderate / High / Critical thresholds defined?

The four risk levels are fixed score bands. A score is assigned to exactly one level based on where it falls:

LevelScoreMeaning
LOW0.0 – 2.9Sparse or predominantly beneficial evidence. No active safety alerts.
MODERATE3.0 – 5.4Mixed signals — some risk alongside benefit. Caution at high doses or in sensitive groups.
HIGH5.5 – 7.4Multiple studies or regulatory alerts documenting adverse effects. Professional oversight recommended.
CRITICAL7.5 – 10Regulatory restrictions in one or more major jurisdictions. Serious documented harm. Avoid without specialist supervision.

Thresholds are fixed constants (GIRI_Score_Utils::LEVEL_THRESHOLDS). They do not change per ingredient and are never subject to editorial adjustment.

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