ოთხშაბათი, აპრილი 15, 2026
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Global Ingredient Risk Index Specialty

Broccoli Powder

Brassica oleracea

Also known as: Cruciferous vegetable powder, Sulforaphane source, Brassica powder

LOW RISK 1.0/10 How?

This ingredient is classified as unclassified risk.

02

Safety Profile

Information not yet available for this ingredient profile.

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03

Interactions

Information not yet available for this ingredient profile.

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04

Evidence and Scientific Findings

Overview

Ingredient Overview

Broccoli powder is a food-derived ingredient rich in sulforaphane and indole-3-carbinol. It is very well tolerated. High doses of cruciferous vegetables can mildly affect thyroid hormone production by interfering with iodine uptake, particularly in iodine-deficient individuals. Very safe at typical supplemental doses.

Classification

Biological and Chemical Classification

Scientific Name
Brassica oleracea
Mechanism

Mechanism of Action

Information not yet available for this ingredient profile.

Clinical Evidence

Clinical Evidence of Effectiveness

Information not yet available for this ingredient profile.

Pharmacokinetics

Pharmacokinetics

Information not yet available for this ingredient profile.

Dosage

Recommended Dosage

Information not yet available for this ingredient profile.

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05

SETI — Scientific Evidence Transparency Index

SETI Score 50/100
Risk Level High risk
Scientific Confidence Low
Evidence Strength Limited
Key Benefit Specialty
Evidence Reviewed 10 PubMed studies
Scientific Confidence Low
Based on study quality, consistency, and recency

Executive Summary — Ingredient Assessment

SETI Score 50/100
Risk Level High risk
Evidence Strength Limited
Main Benefit Specialty
Ingredient Broccoli Powder
Scientific name Brassica oleracea
Scientific Evidence Overview
  • 10 studies reviewed
  • 0 high-quality studies (meta-analysis or RCT)
  • Main clinical benefit observed: Specialty
  • Evidence consistency: High consistency across studies (100%)
Safety Signals
  • No significant safety signals identified in the reviewed literature.
Evidence Strength Limited
Final Scientific Assessment

The available scientific evidence for Broccoli Powder indicates notable safety signals that warrant caution. Use should be considered carefully and monitored, particularly in sensitive populations or alongside other medications.

Ingredient Broccoli Powder
Evidence reviewed 10 peer-reviewed studies (last 10 years)
Scientific name Brassica oleracea
50 /100

Total SETI Score

High risk
Evidence quality 10/40
Evidence consistency 20/20
Safety signals 0/20
Study recency 10/10
Evidence transparency 10/10

Evidence Summary

  • 10 studies reviewed
  • 0 high-quality studies (meta-analysis or systematic review)
  • 0 studies identified benefits or no safety concern (GREEN)
  • 10 studies reported limited or advisory safety evidence (YELLOW)

Evidence Policy

Only peer-reviewed scientific literature indexed in PubMed or comparable databases is included in this evaluation. Commercial websites, blogs, and marketing materials are excluded. All references include direct traceable links to source documents.

Last updated: 06 აპრ 2026, 12:13

Evidence Distribution

10 Other / unclassified
  1. Observational / other LOW evidence YELLOW
    Shaping Kale Morphology and Physiology Using Precision LED Light Recipes. ↗
    PMID 41925031 ↗
    Journal J Exp Bot
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41925031/
    Scandola S et al.. Shaping Kale Morphology and Physiology Using Precision LED Light Recipes.. J Exp Bot. 2026. PMID:41925031.
  2. Observational / other LOW evidence YELLOW
    Two Optimized Methods for Efficient, Stable and Transient Transformation of Broccoli (Brassica oleracea Var. Italica). ↗
    PMID 41901496 ↗
    Journal Plants (Basel)
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41901496/
    Coronado-Martu00edn A et al.. Two Optimized Methods for Efficient, Stable and Transient Transformation of Broccoli (Brassica oleracea Var. Italica).. Plants (Basel). 2026. PMID:41901496.
  3. Observational / other LOW evidence YELLOW
    Red and Far-Red LED Lighting Enhances Protoplast-to-Plant Regeneration in Broccoli (Brassica oleracea var. italica). ↗
    PMID 41901425 ↗
    Journal Plants (Basel)
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41901425/
    Romero-Muu00f1oz M et al.. Red and Far-Red LED Lighting Enhances Protoplast-to-Plant Regeneration in Broccoli (Brassica oleracea var. italica).. Plants (Basel). 2026. PMID:41901425.
  4. Observational / other LOW evidence YELLOW
    Integrated Multi-Omics Analysis Reveals Lipid Metabolism-Mediated Preservation of Postharvest Broccoli Yellowing by Static Magnetic Field. ↗
    PMID 41901389 ↗
    Journal Plants (Basel)
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41901389/
    Lu YB et al.. Integrated Multi-Omics Analysis Reveals Lipid Metabolism-Mediated Preservation of Postharvest Broccoli Yellowing by Static Magnetic Field.. Plants (Basel). 2026. PMID:41901389.
  5. Observational / other LOW evidence YELLOW
    Angiogenesis Suppression via VEGF-VEGFR2 Inhibition and Stromal-Endothelial Crosstalk Disruption by Myrosinase-Activated Broccoli Extract. ↗
    PMID 41900141 ↗
    Journal Molecules
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41900141/
    Naletova I et al.. Angiogenesis Suppression via VEGF-VEGFR2 Inhibition and Stromal-Endothelial Crosstalk Disruption by Myrosinase-Activated Broccoli Extract.. Molecules. 2026. PMID:41900141.
  6. Observational / other LOW evidence YELLOW
    Valorization of By-Products from White Cabbage (Brassica oleracea var. capitata) Processing. ↗
    PMID 41897731 ↗
    Journal Foods
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41897731/
    Dubrovska A et al.. Valorization of By-Products from White Cabbage (Brassica oleracea var. capitata) Processing.. Foods. 2026. PMID:41897731.
  7. Observational / other LOW evidence YELLOW
    In Silico Design and Subsequent Expression of Human Papillomavirus-16 and -18 L1 Vaccine Antigens in Broccoli. ↗
    PMID 41893797 ↗
    Journal Vaccines (Basel)
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41893797/
    Batool N et al.. In Silico Design and Subsequent Expression of Human Papillomavirus-16 and -18 L1 Vaccine Antigens in Broccoli.. Vaccines (Basel). 2026. PMID:41893797.
  8. Observational / other LOW evidence YELLOW
    Potent antioxidant and anticancer efficacy of Brassica oleracea var acephala extracts: a cytomorphological and antidiabetic assessment. ↗
    PMID 41880462 ↗
    Journal Braz J Biol
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41880462/
    Shafi S et al.. Potent antioxidant and anticancer efficacy of Brassica oleracea var acephala extracts: a cytomorphological and antidiabetic assessment.. Braz J Biol. 2026. PMID:41880462.
  9. Observational / other LOW evidence YELLOW
    BnaPAP2.C2 plays a novel inhibitory role in anthocyanin accumulation compared to its paralogs in rapeseed (Brassica napus L.). ↗
    PMID 41877443 ↗
    Journal Plant J
    Year 2026
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41877443/
    Xu L et al.. BnaPAP2.C2 plays a novel inhibitory role in anthocyanin accumulation compared to its paralogs in rapeseed (Brassica napus L.).. Plant J. 2026. PMID:41877443.
  10. Observational / other LOW evidence YELLOW
    In vitro characterization of fiber-rich tropical feedstuffs for pig diets. ↗
    PMID 41923837 ↗
    Journal J Adv Vet Anim Res
    Year 2025
    Study type Observational / other
    Evidence strength LOW evidence
    PubMed link https://pubmed.ncbi.nlm.nih.gov/41923837/
    Nguyen QH et al.. In vitro characterization of fiber-rich tropical feedstuffs for pig diets.. J Adv Vet Anim Res. 2025. PMID:41923837.
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06

Score Transparency

Q × L × D × S × 10 = 1.0 / 10

The GIRI Score is the product of four independently computed evidence components, each normalised to 0–1, then scaled to 0–10. Every component is derived exclusively from peer-reviewed references and regulatory data — no editorial judgement is applied.

Q
Evidence Quantity 0 / 10
0%

0 of 10 approved references (score saturates at 10). More peer-reviewed studies = stronger evidence base.

Method: Q = number of approved references ÷ 10 (capped at 1.0)

L
Evidence Quality 5 / 10
50%

Limited — mostly case reports or animal studies

Method: L = mean study-level weight across approved references. Level 1 (meta-analysis / systematic review) = 1.0; Level 2 (RCT) = 0.8; Level 3 (cohort/case-control) = 0.6; Level 4 (case report) = 0.4; Level 5 (animal / in-vitro) = 0.2.

D
Evidence Direction 5 / 10
Benefit
Risk
50%

Mixed or neutral — roughly equal benefit and risk signals

Method: D = (sum of risk-scored references − sum of benefit-scored references) ÷ total evidence score, then scaled from [−1, 1] to [0, 1]. 0.0 = pure benefit; 0.5 = neutral; 1.0 = pure risk.

S
Safety Signals 5 / 10
50%

One or more monitoring-level safety signals active

Method: S = 0.5 (neutral baseline) + sum of active signal severity deltas ÷ 10. Severity deltas: Critical = +2.0, High = +1.5, Moderate = +1.0, Low = +0.5. Capped at 1.0.

0Q × 5L × 5D × 5S = 1.0 / 10

Final GIRI Score for Broccoli Powder. Risk level thresholds: Low 0–3.0 · Moderate 3.0–5.5 · High 5.5–7.5 · Critical 7.5–10.

Full methodology & data sources

The GIRI Score is computed entirely from structured data — no editorial scoring or subjective weighting is applied at any step.

  • References: Only approved references are counted. Each reference is assigned an evidence level (L1–L5) and a direction (risk / neutral / benefit) by the reference manager or AI classifier.
  • Safety Signals: Sourced from regulatory agencies (FDA, EMA, Health Canada, TGA, and others) and pharmacovigilance databases. Only active signals count toward the score.
  • Formula version: GIRI Score v3.7.0 — Q × L × D × S × 10.
  • Limitations: The score reflects published evidence and recorded signals as of the last update date. It is not a clinical risk assessment and should not replace advice from a qualified healthcare professional.
07

Risk Level Classification

LOW RISK 1.0/10

Based on available regulatory signals and scientific evidence, this ingredient presents a low safety concern under normal conditions of use.

LOW
0–3.0
MODERATE
3.0–5.5
HIGH
5.5–7.5
CRITICAL
7.5–10
1.0

The score pin shows exactly where this ingredient falls on the fixed risk scale.

What drove the Low classification for Broccoli Powder

GIRI Score 1.0 / 10

A score of 1.0 places this ingredient in the Low band. Thresholds: Low 0–3.0 · Moderate 3.0–5.5 · High 5.5–7.5 · Critical 7.5–10.

Evidence Quantity (Q) 0 / 10 refs

0 approved references.

Evidence Quality (L) 50%

Limited — mostly case reports or animal studies (Level 4–5).

Evidence Direction (D) 50% toward risk

Neutral or mixed — benefit and risk signals roughly balanced.

Safety Signals (S) 0 active signals

No active signals — S component is at neutral baseline (0.5), contributing no extra risk weight.

Regulatory Status No restrictions found

No major regulatory restrictions or advisories recorded across monitored jurisdictions (FDA, EMA, Health Canada, TGA, and others).

How are the Low / Moderate / High / Critical thresholds defined?

The four risk levels are fixed score bands. A score is assigned to exactly one level based on where it falls:

LevelScoreMeaning
LOW0.0 – 2.9Sparse or predominantly beneficial evidence. No active safety alerts.
MODERATE3.0 – 5.4Mixed signals — some risk alongside benefit. Caution at high doses or in sensitive groups.
HIGH5.5 – 7.4Multiple studies or regulatory alerts documenting adverse effects. Professional oversight recommended.
CRITICAL7.5 – 10Regulatory restrictions in one or more major jurisdictions. Serious documented harm. Avoid without specialist supervision.

Thresholds are fixed constants (GIRI_Score_Utils::LEVEL_THRESHOLDS). They do not change per ingredient and are never subject to editorial adjustment.

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