Global Ingredient Risk Index Metabolic

Beetroot Powder

Beta vulgaris (beet root, standardized nitrate)

Also known as: beet root powder, beetroot extract, dietary nitrate, beet juice powder

25 მარ 2026

LOW RISK 2.0/10 How?

This ingredient is classified as unclassified risk (GIRI score: 2.0/10).

Known Safety Concerns

Beeturia (benign red urine/stool) -- common
High oxalate content -- caution in kidney stone history
May lower blood pressure -- caution in hypotension
Antibacterial mouthwash negates effect

Contraindications

Beeturia (benign red urine/stool) -- common
High oxalate content -- caution in kidney stone history

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Information not yet available for this ingredient profile.

Beetroot powder is standardized for dietary nitrate content, converted to nitric oxide via the enterosalivary pathway. Well-evidenced for blood pressure reduction and athletic endurance. Use of antibacterial mouthwash negates effect.

Scientific Name: Beta vulgaris (beet root, standardized nitrate)

Information not yet available for this ingredient profile.

SETI Score 50/100

Risk Level High risk

Scientific Confidence Low

Evidence Strength Limited

Key Benefit Metabolic

Key Safety Concern Beeturia (benign red urine/stool) -- common

Evidence Reviewed 10 PubMed studies

Scientific Confidence Low

Based on study quality, consistency, and recency

Executive Summary — Ingredient Assessment

SETI Score 50/100

Risk Level High risk

Evidence Strength Limited

Main Benefit Metabolic

Main Safety Concern Beeturia (benign red urine/stool) -- common

Ingredient Beetroot Powder

Scientific name Beta vulgaris (beet root, standardized nitrate)

Scientific Evidence Overview

10 studies reviewed
0 high-quality studies (meta-analysis or RCT)
Main clinical benefit observed: Metabolic
Evidence consistency: High consistency across studies (100%)

Safety Signals

Beeturia (benign red urine/stool) -- common
High oxalate content -- caution in kidney stone history
May lower blood pressure -- caution in hypotension
Antibacterial mouthwash negates effect

Evidence Strength Limited

Final Scientific Assessment

The available scientific evidence for Beetroot Powder indicates notable safety signals that warrant caution. Use should be considered carefully and monitored, particularly in sensitive populations or alongside other medications.

Ingredient Beetroot Powder

Evidence reviewed 10 peer-reviewed studies (last 10 years)

Scientific name Beta vulgaris (beet root, standardized nitrate)

50 /100

Total SETI Score

High risk

Evidence quality	10/40
Evidence consistency	20/20
Safety signals	0/20
Study recency	10/10
Evidence transparency	10/10

Evidence Summary

10 studies reviewed
0 high-quality studies (meta-analysis or systematic review)
0 studies identified benefits or no safety concern (GREEN)
10 studies reported limited or advisory safety evidence (YELLOW)

Evidence Policy

Only peer-reviewed scientific literature indexed in PubMed or comparable databases is included in this evaluation. Commercial websites, blogs, and marketing materials are excluded. All references include direct traceable links to source documents.

Last updated: 25 მარ 2026, 23:16

Evidence Distribution

10 Other / unclassified

Observational / other LOW evidence YELLOW
Impact of colostrum-derived whey and beetroot powder on the nutritional, rheological and sensory characteristics of set-type yogurt. ↗

PMID 41737702 ↗

Journal J Food Sci Technol

Year 2026

Study type Observational / other

Evidence strength LOW evidence

PubMed link https://pubmed.ncbi.nlm.nih.gov/41737702/

Mehra R et al.. Impact of colostrum-derived whey and beetroot powder on the nutritional, rheological and sensory characteristics of set-type yogurt.. J Food Sci Technol. 2026. PMID:41737702.
Observational / other LOW evidence YELLOW
The dose-response effects of nitrate-rich beetroot ingestion on cardiovascular and endothelial function: a randomised controlled trial. ↗

PMID 41704173 ↗

Journal Food Funct

Year 2026

Study type Observational / other

Evidence strength LOW evidence

PubMed link https://pubmed.ncbi.nlm.nih.gov/41704173/

McLellan AG et al.. The dose-response effects of nitrate-rich beetroot ingestion on cardiovascular and endothelial function: a randomised controlled trial.. Food Funct. 2026. PMID:41704173.
Observational / other LOW evidence YELLOW
Beetroot Powder as Natural Colorant in Fresh Pork Sausages: Impacts on Consumer Liking, Emotional Responses, and Identification of Purchasing Drivers. ↗

PMID 41227684 ↗

Journal Foods

Year 2025

Study type Observational / other

Evidence strength LOW evidence

PubMed link https://pubmed.ncbi.nlm.nih.gov/41227684/

Willig R et al.. Beetroot Powder as Natural Colorant in Fresh Pork Sausages: Impacts on Consumer Liking, Emotional Responses, and Identification of Purchasing Drivers.. Foods. 2025. PMID:41227684.
Observational / other LOW evidence YELLOW
Formulations of novel microbial medium from beetroot powder: a sustainable substitute for commercial Man-de-Rogosa Sharp agar (MRS) in cultivating lactic acid bacteria. ↗

PMID 41075044 ↗

Journal World J Microbiol Biotechnol

Year 2025

Study type Observational / other

Evidence strength LOW evidence

PubMed link https://pubmed.ncbi.nlm.nih.gov/41075044/

Oussama B et al.. Formulations of novel microbial medium from beetroot powder: a sustainable substitute for commercial Man-de-Rogosa Sharp agar (MRS) in cultivating lactic acid bacteria.. World J Microbiol Biotechnol. 2025. PMID:41075044.
Observational / other LOW evidence YELLOW
Acute effects of beetroot juice vs. creatine supplementation on maximal strength, autonomic regulation, and muscle oxygenation during incremental resistance exercise. ↗

PMID 41048226 ↗

Journal Biol Sport

Year 2025

Study type Observational / other

Evidence strength LOW evidence

PubMed link https://pubmed.ncbi.nlm.nih.gov/41048226/

Salem A et al.. Acute effects of beetroot juice vs. creatine supplementation on maximal strength, autonomic regulation, and muscle oxygenation during incremental resistance exercise.. Biol Sport. 2025. PMID:41048226.
Observational / other LOW evidence YELLOW
Comparative Assessment of Matrix Integration Dynamics Between Beetroot Powder and Paste in Wheat-Based Cupcake Formulations. ↗

PMID 40927045 ↗

Journal Food Sci Nutr

Year 2025

Study type Observational / other

Evidence strength LOW evidence

PubMed link https://pubmed.ncbi.nlm.nih.gov/40927045/

Agyei-Poku B et al.. Comparative Assessment of Matrix Integration Dynamics Between Beetroot Powder and Paste in Wheat-Based Cupcake Formulations.. Food Sci Nutr. 2025. PMID:40927045.
Observational / other LOW evidence YELLOW
Red Beetroot Skin Powder Addition as a Multifunctional Ingredient in Nougat. ↗

PMID 40563310 ↗

Journal Antioxidants (Basel)

Year 2025

Study type Observational / other

Evidence strength LOW evidence

PubMed link https://pubmed.ncbi.nlm.nih.gov/40563310/

Constantin OE et al.. Red Beetroot Skin Powder Addition as a Multifunctional Ingredient in Nougat.. Antioxidants (Basel). 2025. PMID:40563310.
Observational / other LOW evidence YELLOW
Low Glycemic Index Biscuits Enriched with Beetroot Powder as a Source of Betaine and Mineral Nutrients. ↗

PMID 40077517 ↗

Journal Foods

Year 2025

Study type Observational / other

Evidence strength LOW evidence

PubMed link https://pubmed.ncbi.nlm.nih.gov/40077517/

Mitrevski J et al.. Low Glycemic Index Biscuits Enriched with Beetroot Powder as a Source of Betaine and Mineral Nutrients.. Foods. 2025. PMID:40077517.
Observational / other LOW evidence YELLOW
An assessment of laboratory changes during autologous whole blood transfusion training: A prospective, observational study. ↗

PMID 40021807 ↗

Journal Transfusion

Year 2025

Study type Observational / other

Evidence strength LOW evidence

PubMed link https://pubmed.ncbi.nlm.nih.gov/40021807/

Schauer SG et al.. An assessment of laboratory changes during autologous whole blood transfusion training: A prospective, observational study.. Transfusion. 2025. PMID:40021807.
Observational / other LOW evidence YELLOW
Enterotype-Specific Effects of Red Beetroot (Beta vulgaris L.) Powder and Betanin on Human Gut Microbiota: A Preliminary Study Based on In Vitro… ↗

PMID 39598189 ↗

Journal Life (Basel)

Year 2024

Study type Observational / other

Evidence strength LOW evidence

PubMed link https://pubmed.ncbi.nlm.nih.gov/39598189/

Ko GP et al.. Enterotype-Specific Effects of Red Beetroot (Beta vulgaris L.) Powder and Betanin on Human Gut Microbiota: A Preliminary Study Based on In Vitro Fecal Fermentation Model.. Life (Basel). 2024. PMID:39598189.

Q × L × D × S × 10 = 2.0 / 10

The GIRI Score is the product of four independently computed evidence components, each normalised to 0–1, then scaled to 0–10. Every component is derived exclusively from peer-reviewed references and regulatory data — no editorial judgement is applied.

0 of 10 approved references (score saturates at 10). More peer-reviewed studies = stronger evidence base.

Method: Q = number of approved references ÷ 10 (capped at 1.0)

50%

Limited — mostly case reports or animal studies

Method: L = mean study-level weight across approved references. Level 1 (meta-analysis / systematic review) = 1.0; Level 2 (RCT) = 0.8; Level 3 (cohort/case-control) = 0.6; Level 4 (case report) = 0.4; Level 5 (animal / in-vitro) = 0.2.

Benefit

Risk

50%

Mixed or neutral — roughly equal benefit and risk signals

Method: D = (sum of risk-scored references − sum of benefit-scored references) ÷ total evidence score, then scaled from [−1, 1] to [0, 1]. 0.0 = pure benefit; 0.5 = neutral; 1.0 = pure risk.

50%

One or more monitoring-level safety signals active

Method: S = 0.5 (neutral baseline) + sum of active signal severity deltas ÷ 10. Severity deltas: Critical = +2.0, High = +1.5, Moderate = +1.0, Low = +0.5. Capped at 1.0.

0Q × 5L × 5D × 5S = 2.0 / 10

Final GIRI Score for Beetroot Powder. Risk level thresholds: Low 0–3.0 · Moderate 3.0–5.5 · High 5.5–7.5 · Critical 7.5–10.

Full methodology & data sources

The GIRI Score is computed entirely from structured data — no editorial scoring or subjective weighting is applied at any step.

References: Only approved references are counted. Each reference is assigned an evidence level (L1–L5) and a direction (risk / neutral / benefit) by the reference manager or AI classifier.
Safety Signals: Sourced from regulatory agencies (FDA, EMA, Health Canada, TGA, and others) and pharmacovigilance databases. Only active signals count toward the score.
Formula version: GIRI Score v3.7.0 — Q × L × D × S × 10.
Limitations: The score reflects published evidence and recorded signals as of the last update date. It is not a clinical risk assessment and should not replace advice from a qualified healthcare professional.

LOW RISK 2.0/10

Based on available regulatory signals and scientific evidence, this ingredient presents a low safety concern under normal conditions of use.

LOW
0–3.0

MODERATE
3.0–5.5

HIGH
5.5–7.5

CRITICAL
7.5–10

2.0

The score pin shows exactly where this ingredient falls on the fixed risk scale.

What drove the Low classification for Beetroot Powder

A score of 2.0 places this ingredient in the Low band. Thresholds: Low 0–3.0 · Moderate 3.0–5.5 · High 5.5–7.5 · Critical 7.5–10.

0 approved references.

Limited — mostly case reports or animal studies (Level 4–5).

Neutral or mixed — benefit and risk signals roughly balanced.

No active signals — S component is at neutral baseline (0.5), contributing no extra risk weight.

No major regulatory restrictions or advisories recorded across monitored jurisdictions (FDA, EMA, Health Canada, TGA, and others).

How are the Low / Moderate / High / Critical thresholds defined?

The four risk levels are fixed score bands. A score is assigned to exactly one level based on where it falls:

Level	Score	Meaning
LOW	0.0 – 2.9	Sparse or predominantly beneficial evidence. No active safety alerts.
MODERATE	3.0 – 5.4	Mixed signals — some risk alongside benefit. Caution at high doses or in sensitive groups.
HIGH	5.5 – 7.4	Multiple studies or regulatory alerts documenting adverse effects. Professional oversight recommended.
CRITICAL	7.5 – 10	Regulatory restrictions in one or more major jurisdictions. Serious documented harm. Avoid without specialist supervision.

Thresholds are fixed constants (GIRI_Score_Utils::LEVEL_THRESHOLDS). They do not change per ingredient and are never subject to editorial adjustment.

← Back to Ingredient Database

Beetroot Powder

Safety Profile

Known Safety Concerns

Contraindications

Interactions

Evidence and Scientific Findings

Ingredient Overview

Biological and Chemical Classification

Mechanism of Action

Clinical Evidence of Effectiveness

Pharmacokinetics

Recommended Dosage

SETI — Scientific Evidence Transparency Index

Executive Summary — Ingredient Assessment

Evidence Summary

Evidence Policy

Evidence Distribution

Score Transparency

Risk Level Classification

What drove the Low classification for Beetroot Powder

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